Reading a DNA sequence: from FASTQ to variants
A sequencing run produces hundreds of millions of short reads and no answer. Here is the standard path from raw FASTQ to a variant call, and the checks that matter.
Read the explainerHome Research Hub
From curiosity
to discovery.
A space for big questions and emerging ideas. Each explainer follows one method end to end and is explicit about where its assumptions stop holding — with sources you can read yourself.
How molecular docking finds a binding pose
Docking predicts where a small molecule sits on a protein and how tightly it holds. Here is how the calculation works, and the limits that decide whether to trust it.
Read the explainerWant to go from reading to doing?
The courses take the same methods and put them in your hands, on data you can download and reanalyse.